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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TSHZ2 All Species: 16.97
Human Site: S743 Identified Species: 46.67
UniProt: Q9NRE2 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NRE2 NP_775756.3 1034 115005 S743 V M D K P V L S P A S T R S A
Chimpanzee Pan troglodytes XP_514730 1034 114957 S743 L M D K P V L S P A S T R S V
Rhesus Macaque Macaca mulatta XP_001097666 1037 115177 S746 V M D K P V L S P T S T R P A
Dog Lupus familis XP_543057 1155 127934 S864 V L D K P G L S P A P T R P A
Cat Felis silvestris
Mouse Mus musculus Q68FE9 1030 114204 P739 V D K P V I S P T S T R P A A
Rat Rattus norvegicus XP_001074194 1033 114566 P742 V D K P V I S P T S T R P A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509428 1037 115085 S747 V I E K P V L S P A P S R P A
Chicken Gallus gallus XP_417506 1036 115062 T746 E K P V L S P T P T P P K P A
Frog Xenopus laevis NP_001165937 1077 118777 P788 M L D K P I Y P T T P M K Q V
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 96.4 81.7 N.A. 90.4 88.6 N.A. 85.5 84 49.1 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 97.4 84.6 N.A. 94.3 93.6 N.A. 91.3 90.1 64.9 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 86.6 86.6 73.3 N.A. 13.3 13.3 N.A. 66.6 13.3 20 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 86.6 80 N.A. 40 40 N.A. 86.6 26.6 46.6 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 45 0 0 0 23 78 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 23 56 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 12 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 12 0 0 0 34 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 12 23 67 0 0 0 0 0 0 0 0 23 0 0 % K
% Leu: 12 23 0 0 12 0 56 0 0 0 0 0 0 0 0 % L
% Met: 12 34 0 0 0 0 0 0 0 0 0 12 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 12 23 67 0 12 34 67 0 45 12 23 45 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 23 56 0 0 % R
% Ser: 0 0 0 0 0 12 23 56 0 23 34 12 0 23 0 % S
% Thr: 0 0 0 0 0 0 0 12 34 34 23 45 0 0 0 % T
% Val: 67 0 0 12 23 45 0 0 0 0 0 0 0 0 23 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _